Adenosine A1 receptor activator T62

Research use only, not for human use.

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[2][3].

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[2][3].(In Vivo):Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect. However it has no effect on ambulation or activity level.

——

Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. Animal Model:Male SpragueDawley rats (250 g) after paw incision surgery Dosage:0.3 μg, 0.5 μg, 1 μg, and 3 μg Administration:Intrathecal administration Result:Produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) was 0.77 (0.63-0.91) μg.

——

Apoptosis

Adenosine Receptor

PDE4

——

——

40312-34-3

291.79

C15H14ClNOS

>98% (HPLC)

——

Nc1sc2CCCCc2c1C(=O)c1ccc(Cl)cc1

——

(-20℃)

With Ice Pack

≥ 2 years